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Which of the following is true of neurotransmitter function?
- Neurotransmitters open ion channels in the postsynaptic membrane
- neurotransmitters are released into the synapse from the cistaerna
- neurotransmitters alter ion channel activity for minutes
- neurotransmitters directl alter ion channels using a second-messenger chemical
- Neurotransmitters diffuse widely in brain to exert changes in metabolism

